Table 4. Regression analysis for age-, sex- and immunosuppressive protocol-adjusted C5 genetic polymorphisms among recipients with ABMR.
SNPs | Model | OR | 95% CIs | P value |
---|---|---|---|---|
rs76339932 | ||||
Additive | 0.93 | 0.26, 3.27 | 0.90 | |
Dominant | 0.93 | 0.26, 3.27 | 0.90 | |
rs12237774 | ||||
Additive | 0.92 | 0.52, 1.63 | 0.78 | |
Dominant | 0.92 | 0.47, 1.79 | 0.81 | |
Recessive | 0.83 | 0.14, 4.89 | 0.83 | |
HET | 0.94 | 0.47, 1.87 | 0.85 | |
HOM | 0.81 | 0.13, 4.85 | 0.82 | |
rs2300931 | ||||
Additive | 1.62 | 0.82, 3.15 | 0.16 | |
Dominant | 1.59 | 0.74, 3.37 | 0.23 | |
Recessive | 4.42 | 0.36, 53.99 | 0.24 | |
HET | 1.44 | 0.65, 3.16 | 0.36 | |
HOM | 4.69 | 0.38, 57.88 | 0.23 | |
rs10985112 | ||||
Additive | 1.03 | 0.29, 3.64 | 0.96 | |
Dominant | 1.03 | 0.29, 3.64 | 0.96 | |
rs2269066 | ||||
Additive | 1.05 | 0.60, 1.81 | 0.88 | |
Dominant | 1.12 | 0.59, 2.13 | 0.73 | |
Recessive | 0.71 | 0.13, 3.94 | 0.69 | |
HET | 1.17 | 0.60, 2.29 | 0.64 | |
HOM | 0.74 | 0.13, 4.19 | 0.74 | |
rs41260544 | ||||
Additive | 1.44 | 0.38, 5.44 | 0.59 | |
Dominant | 1.44 | 0.38, 5.44 | 0.59 | |
rs117287858 | ||||
Additive | 2.13 | 0.29, 15.88 | 0.46 | |
Dominant | 2.13 | 0.29, 15.88 | 0.46 | |
rs2230212 | ||||
Additive | 0.75 | 0.31, 1.78 | 0.51 | |
Dominant | 0.75 | 0.31, 1.78 | 0.51 | |
rs41311867 | ||||
Additive | 1.44 | 0.38, 5.44 | 0.59 | |
Dominant | 1.44 | 0.38, 5.44 | 0.59 | |
rs187517049 | ||||
Additive | 2.73 | 0.23, 31.84 | 0.42 | |
Dominant | 2.73 | 0.23, 31.84 | 0.42 | |
rs12683026 | ||||
Additive | 1.44 | 0.38, 5.44 | 0.59 | |
Dominant | 1.44 | 0.38, 5.44 | 0.59 | |
rs10985122 | ||||
Additive | 1.75 | 0.41, 7.47 | 0.45 | |
Dominant | 1.75 | 0.41, 7.47 | 0.45 | |
rs41309856 | ||||
Additive | 1.23 | 0.34, 4.44 | 0.75 | |
Dominant | 1.23 | 0.34, 4.44 | 0.75 | |
rs144465545 | ||||
Additive | 3.27 | 0.52, 20.59 | 0.21 | |
Dominant | 3.27 | 0.52, 20.59 | 0.21 | |
rs41309850 | ||||
Additive | 1.23 | 0.34, 4.44 | 0.75 | |
Dominant | 1.23 | 0.34, 4.44 | 0.75 | |
rs181763824 | ||||
Additive | 0.64 | 0.06, 6.55 | 0.71 | |
Dominant | 0.64 | 0.06, 6.55 | 0.71 | |
rs2230214 | ||||
Additive | 1.23 | 0.34, 4.44 | 0.75 | |
Dominant | 1.23 | 0.34, 4.44 | 0.75 | |
rs10985126 | ||||
Additive | 1.08 | 0.65, 1.77 | 0.77 | |
Dominant | 1.15 | 0.62, 2.15 | 0.66 | |
Recessive | 0.90 | 0.25, 3.20 | 0.87 | |
HET | 1.19 | 0.62, 2.30 | 0.60 | |
HOM | 0.96 | 0.26, 3.48 | 0.95 | |
rs10985127 | ||||
Additive | 1.08 | 0.65, 1.77 | 0.77 | |
Dominant | 1.15 | 0.62, 2.15 | 0.66 | |
Recessive | 0.90 | 0.25, 3.20 | 0.87 | |
HET | 1.19 | 0.62, 2.30 | 0.60 | |
HOM | 0.96 | 0.26, 3.48 | 0.95 | |
rs28426093 | ||||
Additive | 1.85 | 0.82, 4.15 | 0.14 | |
Dominant | 1.57 | 0.59, 4.18 | 0.37 | |
rs10818499 | ||||
Additive | 1.14 | 0.77, 1.70 | 0.51 | |
Dominant | 1.54 | 0.81, 2.92 | 0.19 | |
Recessive | 0.89 | 0.42, 1.85 | 0.75 | |
HET | 1.81 | 0.89, 3.67 | 0.10 | |
HOM | 1.19 | 0.52, 2.70 | 0.69 | |
rs17216529 | ||||
Additive | 0.89 | 0.51, 1.54 | 0.67 | |
Dominant | 0.94 | 0.49, 1.81 | 0.86 | |
Recessive | 0.52 | 0.10, 2.78 | 0.45 | |
HET | 1.02 | 0.52, 2.03 | 0.95 | |
HOM | 0.53 | 0.10, 2.83 | 0.46 |
SNPs, single nuclear polymorphisms; OR, odds ratio; CIs: confidential intervals.