Skip to main content
. 2017 Oct 10;8(55):94554–94568. doi: 10.18632/oncotarget.21791

Figure 7. XIST positively regulated the Wnt/β-catenin signaling pathway through miR-139-5p.

Figure 7

(A) The inhibitory effect of XIST knockdown on the protein expression levels of Wnt1, β-catenin, and cyclin-D1 in T24 and 5637 cells could be restored by miR-139-5p inhibition. (B) The relative expression levels of Wnt1 mRNA was significantly up-regulated in bladder cancer tissues compared to adjacent normal tissues. (C and D) XIST expression was positively correlated with Wnt1 expression in bladder cancer tissues, while miR-139-5p expression was negatively correlated with Wnt1 expression. *P < 0.05.