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. 2017 Oct 10;8(55):94591–94605. doi: 10.18632/oncotarget.21813

Figure 1. Role of CCR1 in the invasion and metastasis of breast cancer cells.

Figure 1

(A) Representative immunohistochemical staining of CCR1 in breast invasive ductal carcinoma (IDC) and adjacent normal tissue samples. Square N indicates total tissue number. (B) Relative staining scores of CCR1 immunoreactivity in IDC and adjacent normal tissues. Data are mean ± SD. Spot, individual sample; blue horizontal line, mean; red vertical line, error bar. ****, P < 0.0001 (n = 178, paired two-tailed t-test). (C) Relative immunohistochemical staining intensity of CCR1 in ER, PR, HER2, or TN negative (-) or positive (+) samples. Square number indicates total sample number. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2; TN, triple negative (ER-/PR-/HER2-). Values are expressed as mean ± SD. NS, not significant; ****, P < 0.0001; **, P < 0.0220 by one-way ANOVA followed by Sidak’s multiple comparisons test (comparison between normal and cancer groups).