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. 2017 Sep 18;8(55):94635–94649. doi: 10.18632/oncotarget.21831

Figure 6. Epoxyeicosatrienoic acids (EETs).

Figure 6

(A) and dihydroxyeicosatrienoic acids. (DHETs) (B) in ischemic myocardium of MI mice and the ratio of EETs to DHETs (C), as an indicator of t-AUCB treatment efficiency. Before the MI surgery or sham-operated, mice were randomized to receive either drinking-water or t-AUCB (0.2, 1, 5mg/L) for seven days. Measurements were made 24h after MI. The concentration of EETs and DHETs in the ischemic myocardium was measured by reverse-phase HPLC method (A,B), and the sEH activity in the ischemic myocardium was presented by ratio of EETs to DHETs (C). *P<0.05 vs. sham group; #P<0.05 vs. MI group, n=7.