Table 3. Association between SHLP2 and overall risk of cancer and risk of cancer grade, stratified by race.
OR | White | P-value | OR | Black | P-value | |
---|---|---|---|---|---|---|
95% CI | 95% CI | |||||
Univariable | ||||||
No PC | Ref. | Ref. | ||||
Overall PC | 0.95 | 0.93–0.97 | < 0.0001 | 0.996 | 0.99–1.00 | 0.095 |
No PC | Ref. | Ref. | ||||
Low-grade PC | 0.95 | 0.93–0.97 | < 0.001 | 0.99 | 0.90–1.00 | 0.044 |
High-grade PC | 0.95 | 0.93–0.97 | < 0.001 | 1.00 | 0.99–1.00 | 0.598 |
Multivariable* | ||||||
No PC | Ref. | Ref. | ||||
Overall PC | 0.92 | 0.84–0.995 | 0.037 | 0.998 | 0.99–1.01 | 0.706 |
No PC | Ref. | Ref. | ||||
Low-grade PC | 0.91 | 0.83–0.99 | 0.038 | 1.00 | 0.98–1.01 | 0.377 |
High-grade PC | 0.91 | 0.83–0.99 | 0.031 | 1.00 | 0.99–1.02 | 0.671 |
*Adjusted for age, BMI, PSA, year of biopsy, and digital rectal exam.