Table 2. Summary of statistical results.

Statistical model	Group	Number of studies	Q test P value	I2	Model	OR (95% CI)	P value
AA+GA vs. GG	Overall Sepsis	33	P < 0.00001	73%	Random Model	1.35 [1.10, 1.67]	0.005
	Studies with HWE	23	P < 0.00001	78%	Random Model	1.28 [0.99, 1.64]	0.06
	Ethnicity
	Caucasian	14	P = 0.003	58%	Random Model	1.50 [1.13, 2.00]	0.006
	Asian	11	P < 0.00001	83%	Random Model	1.56 [0.97, 2.51]	0.07
	Septic shock	8	P = 0.17	32%	Fixed Model	1.52 [1.18, 1.95]	0.001
	Mortality	16	P = 0.03	45%	Random Model	0.99 [0.71, 1.40]	0.97
AA vs. GA+GG	Overall Sepsis	25	P = 0.002	54%	Random Model	1.14 [0.74, 1.74]	0.55
	Studies with HWE	21	P = 0.006	53%	Random Model	1.09 [0.67, 1.75]	0.74
	Ethnicity
	Caucasian	9	P = 0.58	0%	Fixed Model	1.01 [0.61, 1.66]	0.97
	Asian	9	P < 0.0001	78%	Random Model	1.57 [0.55, 4.49]	0.40
	Septic shock	4	P = 0.55	0%	Fixed Model	2.78 [1.20, 6.40]	0.02
	Mortality	12	P = 0.49	0%	Fixed Model	1.75 [0.97, 3.18]	0.06
AA vs GG	Overall Sepsis	25	P < 0.0001	66%	Random Model	1.13 [0.68, 1.86]	0.64
	Studies with HWE	21	P < 0.0001	67%	Random Model	1.07 [0.60, 1.91]	0.81
	Ethnicity
	Caucasian	9	P = 0.56	0%	Fixed Model	1.06 [0.64, 1.74]	0.83
	Asian	9	P < 0.00001	85%	Random Model	1.56 [0.42, 5.75]	0.51
	Septic shock	4	P = 0.55	0%	Fixed Model	2.84 [1.22, 6.59]	0.02
	Mortality	12	P = 0.50	0%	Fixed Model	1.60 [0.88, 2.92]	0.12
A vs G	Overall Sepsis	27	P < 0.00001	77%	Random Model	1.17 [0.96, 1.42]	0.12
	Studies with HWE	21	P < 0.00001	79%	Random Model	1.13 [0.90, 1.41]	0.30
	Ethnicity
	Caucasian	9	P = 0.59	0%	Fixed Model	1.13 [0.96, 1.32]	0.13
	Asian	11	P < 0.00001	87%	Random Model	1.46 [0.91, 2.32]	0.12
	Septic shock	4	P = 0.66	0%	Fixed Model	1.30 [0.97, 1.75]	0.08
	Mortality	12	P = 0.18	27%	Fixed Model	0.91 [0.72, 1.15]	0.42