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| Study | Randomization | Double-blind | Withdrawals and dropouts | Allocation concealment | Jadad score |
|---|---|---|---|---|---|
| Halgreen, 1986 | 1 | 1 | 0 | 1 | 3 |
| Paris, 1993 | 1 | 1 | 1 | 0 | 3 |
| O’Keefe, 2001 | 1 | 0 | 1 | 0 | 2 |
| Safdi, 2006 | 1 | 1 | 1 | 0 | 3 |
| Whitcomb, 2010 | 1 | 2 | 1 | 1 | 5 |
| Thorat, 2012 | 1 | 2 | 1 | 1 | 5 |
| Seiler, 2013 | 1 | 2 | 1 | 1 | 5 |
