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. 2017 Jul 12;8(56):95206–95222. doi: 10.18632/oncotarget.19199

Figure 6. The combination of teriflunomide and PF477736 is cytotoxic in transformed mouse embryonic fibroblasts.

Figure 6

(A) Flow cytometry analysis for apoptosis / necrosis. Cells were exposed to vehicle, positive control camptothecin (0.1 μM), IC70 TFN (10 μM), IC10 PF477736 (0.7 μM) or their combination, collected and stained with annexin V/7AAD. Results are representative of three independent experiments. (B) Quantitation was performed with FlowJo software. Results are expressed as mean values ± SD of three independent experiments. **p < 0.01, ***p < 0.001 as determined by two-tailed unpaired t-test.