Figure 3. VEGF induces intracellular Ca²⁺ oscillations in breast cancer-derived endothelial colony forming cells.

VEGF (10 ng/mL) elicits heterogeneous repetitive Ca²⁺ transients in five BC-ECFCs recorded from the same microscopic field. The dashed box in the lowermost trace marks the pacemaker increase in [Ca²⁺]_i that features InsP₃-dependent Ca²⁺ spikes. In these and the other figures, VEGF has been administrated during the time period indicated by the black bars placed above the Ca²⁺ traces.