Table 2. Top 30 differentially expressed mRNAs in RA patients compared with healthy controls.
mRNA | P value | Fold changes |
---|---|---|
Up-regulated | ||
CST5 | 0.011015 | 11.7354 |
MYL5 | 0.016609 | 9.437377 |
MTRNR2L2 | 0.017951 | 9.170133 |
ABLIM3 | 0.035346 | 8.106463 |
ATP5A1 | 0.028899 | 8.078051 |
CDK2AP1 | 0.028824 | 8.064926 |
TRAPPC1 | 0.030183 | 7.857362 |
HLA-A | 0.002232 | 7.815082 |
MAP1LC3B | 0.036902 | 7.535449 |
MNDA | 0.039922 | 7.465274 |
CD9 | 0.02348 | 7.367939 |
GABARAPL2 | 0.028315 | 7.146566 |
ATP6V0C | 0.036303 | 7.128572 |
FCGR2A | 0.040717 | 7.009223 |
OSBPL9 | 0.038812 | 6.904492 |
RAB11B | 0.042927 | 6.857076 |
MTRNR2L9 | 0.045445 | 6.854809 |
ND4L | 0.016292 | 6.695147 |
DUSP6 | 0.042244 | 6.100676 |
TLN1 | 0.031514 | 5.967558 |
GNG10 | 0.034438 | 5.903362 |
MLH3 | 0.016582 | 5.829806 |
CDC14B | 0.030726 | 5.664988 |
LOC100130865 | 0.04633 | 5.565929 |
PTPN22 | 0.018824 | 5.555936 |
A_21_P0013791 | 0.029625 | 5.535323 |
FURIN | 0.048091 | 5.514076 |
TCP11L2 | 0.042912 | 5.49967 |
USP17L25 | 0.000509 | 5.468273 |
ND4 | 0.044486 | 5.341476 |
Down-regulated | ||
ACACA | 0.020405 | 4.04911 |
RAB6C-AS1 | 0.028936 | 3.383973 |
DNAH2 | 0.022414 | 3.373326 |
GGCT | 0.037562 | 3.187807 |
TRIP10 | 0.006481 | 3.142754 |
CSF1R | 0.047671 | 3.142102 |
TMEM229B | 0.018878 | 2.677905 |
FILIP1L | 0.008344 | 2.559852 |
A_33_P3244828 | 0.034094 | 2.470736 |
lnc-GRIK1-AS2-1 | 0.022228 | 2.376733 |
BCL6 | 0.030188 | 2.364881 |
INPP5F | 0.046803 | 2.35886 |
NUTM2B | 0.010629 | 2.329807 |
CYP2R1 | 0.019688 | 2.279476 |
NELL1 | 0.003652 | 2.272997 |
A_33_P3398005 | 0.00733 | 2.235301 |
HOXD10 | 0.019771 | 2.223335 |
A_33_P3333364 | 0.01795 | 2.191913 |
ZNF358 | 0.017607 | 2.185415 |
A_33_P3290301 | 0.017789 | 2.182656 |
POU4F3 | 0.04991 | 2.171979 |
lnc-CIB4-1 | 0.017052 | 2.145348 |
TMCO2 | 0.04851 | 2.144128 |
SSX3 | 0.017698 | 2.13033 |
A_33_P3287058 | 0.006785 | 2.109284 |
lnc-RASA1-5 | 0.003285 | 2.092431 |
ADCYAP1R1 | 0.043844 | 2.063525 |
SP140 | 0.041264 | 2.060501 |
lnc-TEX261-2 | 0.034831 | 2.046709 |
MGAT4D | 0.028391 | 2.041796 |