Figure 4. 3D topology of SUM1315 and MDA-MB-231 spheroids by Scanning Electron Microscopy (SEM).

Cells were seeded at 1000 cells per well with 2% Geltrex®, added at Day 1. SEM images were taken at Day 5 with Jeol 6060 LV scanning electron microscope. Scale bars are shown on all images. M=magnification SUM1315 spheroids: (A) M= 270X, (B) M=1500X, (C) M=2500X MDA-MB-231 spheroids at (D) M=200X, (E) M=1300X, (F) M=2000X. ECM= extracellular matrix, Black arrow= cell junction