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. 2017 Aug 24;8(56):95346–95360. doi: 10.18632/oncotarget.20524

Figure 5. Effects of overexpression and knockdown of Botch on apoptosis in brain tissue around hematoma and cultured neurons exposed to OxyHb.

Figure 5

(A) Double staining for TUNEL (green) and DAPI (blue) in vivo. Arrows point to TUNEL-positive cells. Scale bar = 60 μm. Percentage of TUNEL-positive cells was shown. **p = 0.0058 vs sham; ##p = 0.0060 vs ICH + vector; & p = 0.0110 vs ICH + ctr-siRNA. (B) Double staining for TUNEL (green) and DAPI (blue) in vitro. Arrows point to TUNEL-positive cells in cultured neurons. Scale bar = 100 μm. Percentage of TUNEL-positive cells in cultured neurons was shown. **p = 0.0012 vs normal; #p=0.0153 vs OxyHb + vector; && p = 0.0052 vs OxyHb + ctr-siRNA.