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. 2017 Sep 8;8(56):95481–95494. doi: 10.18632/oncotarget.20751

Figure 4. D-4F treatment of stroke in T1DM rats significantly decreases inflammatory factor expression and increases miR-124a expression.

Figure 4

(a) Western blot assay showing that D-4F treatment of T1DM stroke rats decreases TLR4, and nuclear NFκB expression in the ischemic brain compared to PBS treated T1DM stroke control rats (*p<0.05, n=3/group). (b) D-4F treatment significantly increases miR-124a expression in the ischemic brain at 48 hours after stroke (*p<0.05, n=4/group). (c) D-4F treatment significantly decreases MMP9, TLR4 and TNFα gene expression in the ischemic brain compared to PBS treated T1DM stroke control rats at 48 hours after stroke (*p<0.05, n=4/group). Data are represented as mean ± SE.