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. 2017 Sep 23;8(56):95719–95740. doi: 10.18632/oncotarget.21207

Table 1. MicroRNA's expression and their roles in associative learning.

Name of microRNA MicroRNA expression in CR-formation versus control Predicted target genes Functions of target genes
Piriform cortex
mmu-miR-342-5p ↓↓ Neto1
Elfn1
Fgfr2
Gria1
Grin1
Lrrtm2
Nlgn3
Gria1
Elfn1 Excitatory synapses
mmu-miR-324-5p ↑↑ Grin1Lrrtm2Nlgn3Fgfr2
mmu-miR-5128 Fgfr2
mmu-miR-150-5p Csnk1dNlgn2
mmu-miR-3072-3p Slc32a1
mmu-miR-150-5p Nlgn2
mmu-miR-324-5p ↑↑ Slc32a1Nrxn1 Inhibitory synapses
mmu-miR-23b-3p ↑↑ Nrxn1
mmu-miR-133a-3p ↑↑ Iqsec3
mmu-miR-874-5p ↑↑ Ywhaq
mmu-miR-345-5p Gabra4Rgma synapse formation or neuron branching
mmu-miR-149-3p ↑↑ Rgma
mmu-miR-324-5p ↑↑ Ttbk1
mmu-miR-133a-3p ↑↑ Dyrk2 Axon guidance and cytoskeleton
mmu-miR-3072-3p Mark2
mmu-miR-874-5p ↑↑ Gmip
mmu-miR-345-5p Rgma Spines and dendrites
mmu-miR-324-5p ↑↑ Ttbk1
mmu-miR-149-5p ↑↑ RhoaRgma
mmu-miR-149-3p ↑↑ Rhoa
mmu-miR-3072-3p Wnk2 Channels
mmu-miR-149-5p ↑↑ ↑↑
mmu-miR-150-5p Csnk1d Neurite outgrowth
mmu-miR-133a-3p ↑↑ Dyrk2
mmu-miR-149-3p ↑↑ Rgma
mmu-miR-133a-3p ↑↑ Dyrk2 Neuron proliferation and differentiation

↑: log2(CR-formation/Control) <1; ↑↑: 1≦log2(CR-formation/Naïve control) < 2; ↑↑↑: log2(CR-formation/Control) ≧2.