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. 2017 Sep 30;8(56):95865–95879. doi: 10.18632/oncotarget.21430

Figure 4. MST assay confirmed the specific binding of compounds 1-8 and (S)-crizotinib to MTH1.

Figure 4

Measurement of affinity between compounds with MTH1 was carried out by MST in triple. The dissociation constant Kd values were automatically calculated by using the NT Analysis software (Nano Temper Technologies, München, Germany).