Figure 2. Intercellular exchange of mitochondria via nano-tubes in U87^RETO glioblastoma cells.

A and B: mitochondria labeled with red MitoTracker^®, picture A: untreated control, picture B: same cells in response to etoposide added at 5 μg/ml final concentration for a total of 10 days. Pictures B and C: intercellular exchange of mitochondria via nano-tubes as observed by MTT and red MitoTracker^® staining (see arrows). Pictures A and C: untreated controls. Picture E: co-cultivation of mitochondria of U87^RETO cells previously labeled with MitoTracker^® red and green. An exchange of mitochondria via nano-tubes as well as perinuclear arrangement of newly acquired mitochondria around host nucleus are clearly visible (see arrows).