Figure 4. Effect of HBx expression on PERK branch under ER stress condition.
(A) HepG2 cells expressing HBx or control cells were treated for the indicated time with Tg (A) or Tm (B), and p-eIF2a and ATF4 protein levels were measured by Western bots. Relative expression of ATF4 mRNA was detected by RT-PCR assay (C).