Figure 2. The mRNA expression levels of FOXOs in bladder cancer tissue and paracancerous tissue, determined by quantitative real-time polymerase chain reaction (qRT-PCR).

The q-PCR assay was used to test the mRNA expression of FOXO1, FOXO3 and FOXO4 in both normal and tumor tissues, and the results showed that FOXO1, FOXO3 and FOXO4 in tumor tissues had a lower expression than normal tissues; ^*, P < 0.05 compared with paracancerous; FOXO, forkhead box class O.