Figure 3. Treatment with etanercept ameliorates systemic inflammatory disease and normalizes growth in Nlrp3^A350V mice.

(A–C) Injection (s.c.) of etanercept every other day, beginning the day after birth, rescued and normalized growth in Nlrp3^A350V mice during the treatment period. After stopping treatment, survival was extended for an average of 23 days. n = 7 for etanercept-treated Nlrp3^A350V mice and n = 5 for saline-injected Nlrp3^A350V mice.