Table 1.
Highest up-regulated genes in PKCλ/ι−/− podocytes in comparison with WT, which are not regulated in PKCζ−/− podocytes
| Gene | Systematic Name | Fold Change |
|---|---|---|
| Aplp1 | NM_007467 | 367.78 |
| Pdgfd | BC030896 | 269.44 |
| Cxcl12 | NM_013655 | 166.29 |
| Emb | NM_010330 | 134.34 |
| Htatip2 | NM_016865 | 126.05 |
| Six1 | NM_009189 | 86.55 |
| Dlgh3 | NM_016747 | 86.51 |
| Galntl4 | NM_173739 | 81.09 |
| Armcx1 | NM_030066 | 71.40 |
| Flrt3 | NM_178382 | 64.97 |
| Krt18 | NM_010664 | 60.59 |
| Abcg1 | NM_009593 | 59.72 |
| G6pc2 | NM_021331 | 58.98 |
| Tgfb3 | NM_009368 | 50.17 |
| Dpysl4 | NM_011993 | 49.01 |
| Has2 | NM_008216 | 48.59 |
| Lox | NM_010728 | 43.37 |
| Cspg2 | D16263 | 41.96 |
| Msx2 | NM_013601 | 39.62 |
| Foxc2 | NM_013519 | 34.89 |
| Pcsk6 | XM_355911 | 30.30 |
| Cbr3 | NM_173047 | 29.14 |
| Aytl1 | NM_173014 | 27.49 |
| Fbln5 | NM_011812 | 27.00 |
| Antxr1 | NM_054041 | 24.53 |
| Def6 | NM_027185 | 23.91 |
| Tram1l1 | NM_146140 | 23.13 |
| Hist3h2ba | NM_030082 | 20.82 |
| Zfp125 | AJ005350 | 19.73 |
| Smoc2 | NM_022315 | 19.22 |
Fold change is given as the geometric mean for all genes more than two-fold up-regulated in both tested cell clones.