Table 2.
Highest down-regulated genes in PKCλ/ι−/− podocytes in comparison with WT, which are not regulated in PKCζ−/− podocytes
| Gene | Systematic Name | Fold Change |
|---|---|---|
| Pitx1 | NM_011097 | 262.07 |
| Armcx2 | NM_026139 | 250.64 |
| Gbp1 | NM_010259 | 234.54 |
| Sdk1 | NM_177879 | 168.47 |
| Nkx2-3 | NM_008699 | 104.63 |
| Napsa | NM_008437 | 96.27 |
| Gypc | NM_027863 | 91.91 |
| Gcnt1 | NM_010265 | 69.51 |
| Cd74 | NM_010545 | 63.38 |
| Cd302 | NM_025422 | 53.39 |
| Krt8 | NM_031170 | 52.63 |
| Unc93b1 | NM_019449 | 52.00 |
| Tlr1 | NM_030682 | 45.94 |
| Klk1b24 | NM_010643 | 32.84 |
| Tbx15 | NM_009323 | 32.23 |
| Kcnj14 | NM_145963 | 26.07 |
| Lama1 | NM_008480 | 23.63 |
| Ucp2 | NM_011671 | 22.67 |
| Zcchc3 | NM_175126 | 21.17 |
| Casp1 | NM_009807 | 20.24 |
| Ly75 | AK157921 | 18.66 |
| Chst1 | NM_023850 | 18.26 |
| Aqp1 | NM_007472 | 17.55 |
| Hunk | NM_015755 | 16.81 |
| Slc16a13 | NM_172371 | 16.42 |
| Lrrc33 | NM_146069 | 16.33 |
| Ceecam1 | NM_207298 | 14.29 |
| Lbp | NM_008489 | 13.98 |
| Gldc | NM_138595 | 13.30 |
| C3 | NM_009778 | 13.02 |
Fold change is given as the geometric mean for all genes more than two-fold down-regulated in both tested cell clones.