Table 3.
Cox Proportional Hazard Model analysis of covariates that contribute to local failure
| Variable | Univariate hazard ratio (range) | P value | Multivariate hazard ratio (range) | P value |
|---|---|---|---|---|
| Tumor Diameter (≥3 cm) | 8.71 (2.24-33.90) | .002 | 8.11 (2.09-31.50) | .003 |
| Total Dose (30 vs. 25 Gy) | 0.24 (0.07-0.84) | .025 | 0.26 (0.07-0.93) | .038 |
| PTV margin (No vs. Yes) | 1.11 (0.23-5.22) | .899 | ||
| Histology (NSCLC) | Reference = 1 | .732 | ||
| Histology (Breast) | 0.94 (0.11-8.05) | |||
| Histology (Melanoma) | 1.78 (0.34-9.38) | |||
| Histology (Other) | 0.57 (0.11-2.94) |
NSCLC, non-small cell lung cancer; PTV, planning target volume.