Fig. 9. (a) Wound healing assay performed in Transwell® plates as in Fig. 8a. HeLa cells in the lower chamber were treated with 1a-hydrogel or berberine@1a-hydrogel for 4 h and 8 h. Then the upper chamber was removed to allow the wound to recover. Photos were taken at 0 h and 24 h since the induction of wound. Figures are representative of three independent experiments. (b) Percentage of migration of HeLa cells after treatment with 1a-hydrogel or berberine@1a-hydrogel. Data are shown as mean ± SEM from three independent experiments. ****p < 0.0001, *****p < 0.00001.
