Figure 4.

Clinical presentation of experimental and clinical infection of ocular herpesviruses in dogs and cats. (A) Representative CHV-1-associated ocular disease in dogs at day 10 post primary experimental infection, natural infection presenting to the clinic, or at day 7 post reactivation with systemic prednisolone. Experimentally infected dog eyes were stained with lissamine green, although no retention in either dog was observed. Naturally infected dog eyes were stained with fluorescein dye to visualize corneal ulcers; (B) representative feline herpesvirus type 1 FHV-1-associated ocular disease in cats following primary experimental infection at day 4 post infection, with conjunctivitis only and at day 12 post infection, with both corneal ulceration and conjunctivitis, or natural infection presenting to the clinic with both corneal ulceration and conjunctivitis. Cat eyes were stained with fluorescein dye to visualize corneal ulcers.