Table 7.
Effect of melatonin on plasma adipokines after the six-week melatonin intervention.
| Group | C | D | L | M | H |
|---|---|---|---|---|---|
| Adiponectin (µg/mL) | 3.98 ± 0.60 a | 2.14 ± 0.21 b | 2.82 ± 0.75 c | 2.79 ± 0.44 c | 2.90 ± 0.45 c |
| Leptin (ng/mL) | 5.98 ± 2.61 a | 4.94 ± 1.69 a | 3.96 ± 1.40 a,b | 2.08 ± 1.41 b | 2.41 ± 1.91 b |
| leptin/adiponectin ratio | 1.72 ± 0.92 a,b | 2.01 ± 0.65 a | 1.27 ± 0.24 b | 0.53 ± 0.32 c | 0.61 ± 0.68 c |
| Melatonin (pg/mL) | 60.4 ± 7.9 a | 50.3 ± 5.8 b | 120.5 ± 11.7 c | 148.6 ± 17.4 d | 134.8 ± 12.2 d |
All values are the mean ± SD (n = 8). a, b, c, d Values with different superscripts significantly differ between groups (p < 0.05). C, control group; D, diabetic group; L, low-dosage group (10 mg melatonin/kg of body weight (BW)); M, medium-dosage group (20 mg melatonin/kg of BW); and H, high-dosage group (50 mg melatonin/kg of BW).