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. 2017 Oct 15;14(13):1317–1326. doi: 10.7150/ijms.20984

Table 1.

Effects of TIBH on Renal and liver function parameters in acute toxicity test in rats

kidney function parameters in acute toxicity test in rats
Animal groups Sodium (mM/L) Potassium (mM/L) Chloride
(mM/L)
Carbon dioxide(mM/L) Urea
(mM/L)
Creatinine (µM/L)
Normal control 141.32 ± 0.33 5.40 ± 0.61 101.45 ± 0.88 31.67 ± 0.88 8.1 ± 0.68 27.67 ± 1.43
TIBH (300 mg/kg) 142.56 ± 0.37 5.43 ± 0.26 102.98 ± 0.33 33.20 ± 0.51 7.41 ± 0.73 27.33 ± 0.67
TIBH (2000mg/kg) 143.09 ± 0.51 5.5 ± 0.65 103.75 ± 0.88 32.05 ± 0.65 9.3 ± 0.47 28.58 ± 1.0
Liver function parameters in acute toxicity test in rats
Animal groups Albumin (g/L) Total bilirubin (µM/L) Alkaline phosphatase (IU/L) Alanine amino
Transaminase (IU/L)
G-Glutaml. Transferase (IU/L)
Normal control 40.69 ± 0.88 < 2 232 ± 9.87 64.25 ± 7.8 -1.3 ± 0.6
TIBH (300 mg/kg) 43.35 ± 1.2 < 2 191 ± 12.73 65.67 ± 5.4 -2.1 ± 0.2
TIBH (2000mg/kg) 45.61 ± 1.45 < 2 205 ± 10.35 68.55 ± 8.68 -2.6 ± 0.5

All values are expressed as mean ± SD (n = 6). * Shows the significant value was set at p < 0.05, compared with control group.