Table 1.
kidney function parameters in acute toxicity test in rats | ||||||||||
Animal groups | Sodium (mM/L) | Potassium (mM/L) | Chloride (mM/L) |
Carbon dioxide(mM/L) | Urea (mM/L) |
Creatinine (µM/L) | ||||
Normal control | 141.32 ± 0.33 | 5.40 ± 0.61 | 101.45 ± 0.88 | 31.67 ± 0.88 | 8.1 ± 0.68 | 27.67 ± 1.43 | ||||
TIBH (300 mg/kg) | 142.56 ± 0.37 | 5.43 ± 0.26 | 102.98 ± 0.33 | 33.20 ± 0.51 | 7.41 ± 0.73 | 27.33 ± 0.67 | ||||
TIBH (2000mg/kg) | 143.09 ± 0.51 | 5.5 ± 0.65 | 103.75 ± 0.88 | 32.05 ± 0.65 | 9.3 ± 0.47 | 28.58 ± 1.0 | ||||
Liver function parameters in acute toxicity test in rats | ||||||||||
Animal groups | Albumin (g/L) | Total bilirubin (µM/L) | Alkaline phosphatase (IU/L) | Alanine amino Transaminase (IU/L) |
G-Glutaml. Transferase (IU/L) | |||||
Normal control | 40.69 ± 0.88 | < 2 | 232 ± 9.87 | 64.25 ± 7.8 | -1.3 ± 0.6 | |||||
TIBH (300 mg/kg) | 43.35 ± 1.2 | < 2 | 191 ± 12.73 | 65.67 ± 5.4 | -2.1 ± 0.2 | |||||
TIBH (2000mg/kg) | 45.61 ± 1.45 | < 2 | 205 ± 10.35 | 68.55 ± 8.68 | -2.6 ± 0.5 | |||||
All values are expressed as mean ± SD (n = 6). * Shows the significant value was set at p < 0.05, compared with control group.