Table 1.
Physiologic variables during hemorrhagic shock
| Variables | UCCAO-+HS-+WBC- | UCCAO++HS-+WBC- | UCCAO-+HS++WBC- | UCCAO-+HS++WBC+ | UCCAO++HS++WBC- | UCCAO++HS++WBC+ |
|---|---|---|---|---|---|---|
| 1 min before HS/Sham intervention | ||||||
| Tco (oC) | 36.2±0.5 | 36.3±0.4 | 36.3±0.4 | 36.4±0.8 | 36.4±0.6 | 36.3±0.4 |
| Tb (oC) | 36.1±0.4 | 36.0±0.3 | 36.4±0.5 | 36.5±0.7 | 36.3±0.5 | 36.5±0.3 |
| MABP (mmHg) | 86.0±3.0 | 81.0±4.0 | 79.0±5.0 | 89.0±7.0 | 83.0±3.0 | 83.0±2.0 |
| CBF (%) | 98.0±4.0 | 97.0±5.0 | 99.0±4.0 | 97.0±5.0 | 93.0±6.0 | 99.0±5.0 |
| 60 min after HS/sham intervention | ||||||
| Tco (oC) | 36.4±0.4 | 36.5±0.5 | 36.6±0.6 | 36.3±0.7 | 36.6±0.6 | 36.8±0.5 |
| Tb (oC) | 36.3±0.6 | 36.4±0.4 | 36.2±0.4 | 36.0±0.8 | 36.2±0.5 | 36.3±0.4 |
| MABP (mmHg) | 85.0±2.0 | 82.0±4.0 | 22.0±1.0* | 18.0±3.0* | 17.0±3.0* | 21.0±2.0* |
| CBF (%) | 93.0±5.0 | 70.0±3.0* | 52.0±5.0* | 50.0±6.0* | 18.0±4.0*,+ | 16.0±3.0*,+ |
| 90 min after HS/sham intervention | ||||||
| Tco (oC) | 36.3±0.4 | 36.4±0.3 | 36.2±0.6 | 36.5±0.8 | 36.6±0.5 | 36.4±0.7 |
| Tb (oC) | 36.1±0.5 | 36.0±0.5 | 36.5±0.4 | 36.2±0.6 | 36.5±0.6 | 36.3±0.6 |
| MABP (mmHg) | 88.0±5.0 | 86.0±6.0 | 84.0±6.0 | 87.0±6.0 | 85.0±5.0 | 87.0±6.0 |
| CBF (%) | 100.0±6.0 | 97.0±7.0 | 98.0±6.0 | 102.0±9.0 | 99.0±7.0 | 98.0±9.0 |
| 120 min after HS/sham intervention | ||||||
| Tco (oC) | 36.5±0.6 | 36.3±0.5 | 36.6±0.5 | 33.5±0.8* | 36.3±0.4 | 33.7±0.7* |
| Tb (oC) | 36.4±0.3 | 36.2±0.4 | 36.3±0.6 | 33.2±0.7* | 36.2±0.6 | 33.3±0.6* |
| MABP (mmHg) | 89.0±7.0 | 91.1±0.8 | 87.0±7.0 | 89.0±5.0 | 88.0±6.0 | 90.0±6.0 |
| CBF (%) | 99.0±8.0 | 93.0±0.7 | 101.0±8.0 | 100.0±7.0 | 98.0±5.0 | 97.0±7.0 |
Tco = core body temperature; Tb = brain temperature; MABP = mean arterial pressure; CBF = cerebral blood flow; UCCAO- = no unilateral common carotid artery occlusion; HS-= no hemorrhagic shock; WBC-= no whole body cooling; HS+ hemorrhagic shock; WBC+= whole body cooling; UCCAO+= unilateral common carotid artery occlusion. Data are means±S.D. (n=12 per group). *P<0.05, compared with (UCCAO- + HS- + WBC-) group rats; +P<0.05, compared with (UCCAO- + HS+ + WBC-) or (UCCAO- + HS+ + WBC+) group rats.