Table 1.
Ocular manifestations and outcomes of antiviral therapy of 12 patients with CMV retinitis
| No. | Involved eye | Presenting VA (LogMAR) | Involved zone | Sizes of lesions | KP | Anterior chamber inflammation | Vitritis | CMV peak in the blood | CMV copies in vitreous | No. of IVTG | Final VA (LogMAR) | Outcomes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | OD | +0.1 | 3 | <10% | Yes | Yes | Yes | 7.3 × 103 | undetectable | 8 | 0.0 | Improvement |
| OS | +0.1 | 3 | <10% | No | Yes | Yes | undetectable | 17 | 0.0 | Improvement | ||
| 2 | OD | +2.6 | 1,2,3 | >50% | No | No | No | 1.9 × 105 | 7.23 × 104 | 13 | +1.0 | Stabilization |
| OS | +2.6 | 1,2,3 | >50% | No | No | No | 8.65 × 103 | 13 | +1.0 | Improvement | ||
| 3 | OD | +0.2 | 3 | <10% | No | No | No | 2.78 × 106 | undetectable | 2 | +0.1 | Stabilization |
| 4 | OD | +0.2 | 1,2,3 | >50% | No | No | Yes | 2.4 × 104 | 1.00 × 106 | 25 | +1.0 | Deterioration |
| OS | +0.1 | 1,2 | 10%–50% | No | No | Yes | 2.34 × 105 | 13 | +0.4 | Deterioration | ||
| 5 | OD | +0.1 | 1 | <10% | No | No | No | 1.0 × 104 | 5.52 × 102 | 7 | −0.1 | Improvement |
| OS | +0.1 | 2 | <10% | Yes | Yes | Yes | 5.63 × 102 | 21 | 0.0 | Improvement | ||
| 6 | OD | 0.0 | 3 | <10% | No | No | Yes | 4.4 × 103 | undetectable | 4 | 0.0 | Stabilization |
| 7 | OS | 0.0 | 3 | <10% | Yes | Yes | Yes | 9.0 × 103 | 5.34 × 102 | 4 | 0.0 | Stabilization |
| 8 | OD | +0.4 | 1,2,3 | >50% | No | No | No | 3.32 × 106 | 28 | +2.9 | Deterioration | |
| OS | +0.5 | 1,2,3 | >50% | No | No | No | 3.68 × 106 | 29 | +2.9 | Deterioration | ||
| 9 | OS | +0.3 | 1,2 | 10%–50% | No | No | No | 3.5 × 103 | 6.79 × 103 | 9 | +0.1 | Improvement |
| 10 | OS | +0.2 | 2 | 10%–50% | No | No | No | 6.24 × 102 | 3 | +0.2 | Stabilization | |
| 11 | OD | +0.1 | 3 | <10% | No | No | No | 4.4 × 104 | 4.18 × 104 | 8 | +0.5 | Deterioration |
| OS | +0.2 | 2,3 | 10%–50% | Yes | Yes | Yes | 1.85 × 105 | 8 | +2.6 | Deterioration | ||
| 12 | OD | +1.0 | 1,2,3 | >50% | No | No | Yes | 3.3 × 103 | 2.79 × 106 | 17 | +2.7 | Deterioration |
| OS | +0.2 | 1,2,3 | >50% | No | No | Yes | 2.24 × 106 | 17 | +2.6 | Deterioration |
VA: visual acuity; Presenting VA: vision acuity of the involved eye when CMV retinitis was first diagnosed; Final VA: vision acuity at the last visit; KP: keratic precipitates; OU: both eyes; OD: right eye; OS: left eye; involved zone of retinal lesions: zone 1 was in the area within 1500 μm of the optic nerve or within 3000 μm of the fovea, zone 2 was located from the edge of zone 1 anteriorly to the vortex veins and zone 3 was located anteriorly from zone 2 to the ora serrata. Sizes of lesions were classified as involving <10%, 10% to 50%, or >50% of the total retinal area based on the fundus photograph. Patient numbers correspond to those in Table 1