Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 15;1:16012. doi: 10.1038/npjvaccines.2016.12

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Boosting of BCG protective immunity by CysVac2. C57BL/6 mice (n=5) were vaccinated with BCG s.c. or left unvaccinated and 12 weeks later boosted s.c. with 3 doses of CysVac2/MPL-DDA or with MPL-DDA alone. Six weeks after last boost, mice were challenged with ~100 CFU of M. tuberculosis by aerosol route and after 4 weeks the bacterial load enumerated in the lung (a) and spleen (b). Data are combined from two experiments and presented as the Log₁₀ CFU difference for each individual mouse compared with the mean of unvaccinated animals. The significance of differences between groups was determined by one-way analysis of variance (ANOVA) (*P<0.05; **P<0.01; ***P<0.001).