Table 2.
Patients | Surgical procedure | Pathogen | DAP Reason | DAP dosage (mg/kg/day) | DAP duration (days) | Total parental antibiotics (days) | Total time under DAP (%) | Adverse effects | Outcome | Follow-up (months) |
---|---|---|---|---|---|---|---|---|---|---|
1 | two-stage reimplantation | MRSA | intolerance | 10 | 10 | 13 | 77 | none | success | 26 |
2 | two-stage reimplantation | MRSA | intolerance | 8.3 | 18 | 35 | 51 | none | success | 27 |
3 | two-stage reimplantation | MRCoNS | CKD stage 5 | 3.3 | 12 | 15 | 80 | none | success | 25 |
4 | DAIR | MRCoNS | intolerance | 8.3 | 23 | 23 | 100 | none | success | 41 |
5 | two-stage reimplantation | MRSA | CKD stage 3 | 7.7 | 13 | 13 | 100 | none | success | 23 |
6 | DAIR | MRSA | teicoplanin failure | 10.6 | 11 | 21 | 52 | AST elevation | success | 25 |
7 | two-stage reimplantation | MRCoNS | intolerance | 8.3 | 12 | 26 | 46 | none | success | 27 |
8 | two-stage reimplantation | MRSA | intolerance | 7.2 | 18 | 49 | 37 | none | success | 24 |
9 | DAIR | MRSA | vancomycin MIC >1.5 mg/L | 10 | 27 | 32 | 84 | none | success | 26 |
10 | two-stage reimplantation | MRSA | empirical | 6.3 | 21 | 33 | 64 | none | failure | 24 |
11 | two-stage reimplantation | MRCoNS | intolerance | 10 | 13 | 36 | 36 | none | success | 34 |
12 | two-stage reimplantation | MRSA | teicoplanin failure | 6.7 | 14 | 39 | 36 | none | success | 36 |
13 | DAIR | MRSA | intolerance | 7.4 | 14 | 20 | 70 | none | success | 29 |
14 | two-stage reimplantation | MRCoNS | empirical | 8.3 | 16 | 22 | 73 | none | success | 36 |
15 | DAIR | MRSA | empirical | 8.3 | 26 | 66 | 39 | none | failure | 34 |
16 | two-stage reimplantation | MRCoNS | empirical | 10.6 | 11 | 19 | 58 | none | success | 42 |
DAP Daptomycin, MRSA Methicillin-resistant Staphylococcus aureus, MRCoNS Methicillin-resistant coagulase-negative staphylococci CKD, chronic kidney disease, MIC Minimum inhibitory concentration, AST Aspartate aminotransferase; intolerance, allergy to glycopeptide or phlebitis