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Schematic representation of the different permethylation techniques. (A) Spin-column setup: (1) spin column; (2) NaOH beads; (3) column holder; (4) micro-centrifuge tube; (B) 500 μm i.d. fused-silica capillary setup: (5) 500 μm i.d. fused-silica capillary; (6) syringe; (7) syringe pump.
