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. Author manuscript; available in PMC: 2018 Jan 16.
Published in final edited form as: Methods Enzymol. 2017 Jan 16;585:397–429. doi: 10.1016/bs.mie.2016.11.009

Figure 7.7. Combined top-down and middle-down proteomics approach to identifying IgG glycosylation profile.

Figure 7.7

A Top-down native mass spectrometry of intact IgG to readily identify glycoforms. B Middle-down mass spectrometry to identify peptide backbone and any post-translational modifications. Reproduced with permission (Tran et al., 2016).