Table III.
Enzymes in purine metabolism
| Enzyme or reaction | Abbreviation | EC Number |
|---|---|---|
|
| ||
| Hypoxanthine-guanine phosphoribosyltransferase | HGPRT | 2.4.2.8 |
| GMP synthetase | GMPS | 6.3.5.2 |
| Adenylosuccinate lyase | ASLI | 4.3.2.2 |
| GMP reductase | GMPR | 1.7.1.7 |
| AMP deaminase | AMPD | 3.5.4.6 |
| 5’(3’) Nucleotidase | 3NUC | 3.1.3.31 |
| Diribonucleotide reductase | DRNR | 1.17.4.1 |
| Adenosine deaminase | ADA | 3.5.4.4 |
| DNA polymerase | DNAP | 2.7.7.7 |
| DNases | DNAN | # |
| Guanine hydrolase | GUA | 3.5.4.3 |
| ‘hypoxanthine excretion’ | hx | $ |
| ‘xanthine excretion' | x | $ |
| `uric acid excretion' | ua | $ |
| Phosphoribosylpyrophosphate synthetase | PRPPS | 2.7.6.1 |
| Amidophosphoribosyltransferase | ATASE | 2.4.2.14 |
| Adenine phosphoribosyltransferase | APRT | 2.4.2.7 |
| `pyrimidine synthesis' | PYRS | # |
| IMP dehydrogenase | IMPD | 1.1.1.205 |
| Adenylosuccinate synthetase | ASUC | 6.3.4.4 |
| Methionine adenosyltransferase | MAT | 2.5.1.6 |
| Protein O-methyltransferase | MT | 2.1.1.77, 2.1.1.80, and 2.1.1.100 |
| S-adenosylmethionine decarboxylase | SAMD | 4.1.1.50 |
| 5’-Nucleotidase | 5NUC | 3.1.3.5 |
| RNA polymerase | RNAP | 2.7.7.6 |
| RNases | RNAN | # |
| Xanthine oxidase or xanthine dehydrogenase | XD | 1.17.1.4 and 1.17.3.2 |
#
: Multiple enzymes.
$
: Non-enzymatic reaction.