Table 2.
Correlations of pCR with hematological and immunological factors (n=92a)
| Variables | pCR
|
P-value | |
|---|---|---|---|
| Yes | No | ||
| NLR | |||
| <2.0 | 11 (40.7) | 16 (59.3) | 0.043 |
| ≥2.0 | 13 (20.3) | 51 (79.7) | |
| LYMR | |||
| <0.3 | 12 (19.7) | 49 (80.3) | 0.039 |
| ≥0.3 | 12 (40.0) | 18 (60.0) | |
| CD8+ TIL | |||
| Low | 15 (21.7) | 54 (78.3) | 0.100 |
| High | 9 (39.1) | 14 (60.9) | |
| TIL–NLR | |||
| Low | 6 (30.0) | 14 (70.0) | 0.916 |
| Moderate | 14 (25.5) | 41 (74.5) | |
| High | 4 (25.0) | 12 (75.0) | |
| TIL–LYMR | |||
| Low | 8 (17.0) | 39 (83.0) | 0.038 |
| Moderate | 11 (31.4) | 24 (68.6) | |
| High | 5 (55.6) | 4 (44.4) | |
Note:
a
One patient’s hematological data were not available.
Abbreviations: pCR, pathologic complete response; NLR, neutrophil–lymphocyte ratio; LYMR, lymphocyte ratio; TIL, tumor-infiltrating lymphocyte; TIL–NLR, combination of CD8+ TIL and NLR; TIL–LYMR, combination of CD8+ TIL and LYMR.