Table 1.
Comparison of demographic, clinical and laboratory parameters between RA patients and healthy controls
| Rheumatoid arthritis (n = 37) | Controls (n = 34) | p | |
|---|---|---|---|
| Age (years) | 48.95 ±7.63 | 45.76 ±7.72 | 0.086 |
| Female/Male | 29/8 | 17/17 | 0.012 |
| BMI | 28.55 ±4.46 | 29.08 ±4.20 | 0.608 |
| Duration of the disease (years) | 12.81 ±6.75 | ||
| Morning stiffness (min.) | 111.62 ±79.14 | ||
| Pain (0-10 cm VAS) | 5.81 ±1.72 | ||
| Fatigue (0-10 cm VAS) | 5.86 ±1.58 | ||
| Patients global (0-10 cm VAS) | 5.92 ±1.55 | ||
| Physicians global (0-10 cm VAS) | 5.86 ±1.65 | ||
| Number of the swollen joints (0-28) | 1.70 ±2.22 | ||
| Number of the tender joints (0-28) | 7.08 ±4.84 | ||
| Erythrocyte sedimentation rate (mm/h) | 27.76 ±15.71 | 9.85 ±8.91 | 0.001 |
| C reactive protein (g/dl) | 19.78 ±34.56 | 5.04 ±3.77 | 0.001 |
| Rheumatoid factor (IU/ml) | 99.10 ±126.30 | 10.67 ±0.61 | 0.001 |
| Anti-Cyclic citrullinated peptide (IU/ml) | 285.68 ±303.82 | ||
| Serum LCN-2 (ng/ml) | 803.80 ±508.62 | 597.66 ±182.33 | 0.029 |
| Disease Activity Score 28 | 4.27 ±1.29 | ||
| Health Assessment Questionnaire 20 (0-3) | 31.32 ±9.11 | 3.82 ±5.99 | 0.001 |
| Modified Larsen Score (0-120) | 56.11 ±31.20 |
VAS – Visual Analogue Scale, LCN-2 – Lipocalin 2