Table 3. 68Ga competition studies at pH 3.5: equimolar solutions of HBED, THP or DFO with either DOTA, NOTA, NOTP, TRAP, HBED, THP or DFO, were reacted with 68Ga3+. The RCYs of [68Ga(HBED)], [68Ga(THP)] and [68Ga(DFO)] for each of these reactions are given in the below table.
25 °C |
90 °C |
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HBED | THP | DFO | HBED | THP | |
DOTA | 99% HBED | 100% THP | 100% DFO | 96% HBED | 100% THP |
NOTA | 43% HBED | 97% THP | 38% DFO | 32% HBED | 79% THP |
NOTP | 0% HBED | 94% THP | 24% DFO | 0% HBED | 64% THP |
TRAP | 0% HBED | 100% THP | 30% DFO | 0% HBED | 82% THP |
HBED | — | 100% THP | 17% DFO | — | 100% THP |
THP | 0% HBED | — | 0% DFO | 0% HBED | — |