Table 1. Univariate survival analysis of patients with non-CF bronchiectasis.
Characteristics | Survivors (n=60) | Non-survivors (n=9) | P |
---|---|---|---|
Age (years), mean ± SD | 56.8±13.7 | 60.8±15.1 | 0.424 |
Sex (M/F) | 32/28 | 7/2 | 0.281 |
BMI, mean ± SD | 22.3±3.4 | 20.2±2.5 | 0.081 |
Smoking | |||
Never | 50 | 5 | 0.075 |
Ex/current | 10 | 4 | – |
PFT | |||
FVC (L), median (IQR) | 2.0 (1.5–2.5) | 1.4 (0.7–1.8) | 0.004 |
FEV1 (L), median (IQR) | 1.4 (1.1–1.9) | 0.8 (0.4–1.2) | 0.001 |
FEV1/FVC (%), median (IQR) | 75.9 (63.9–81.3) | 65.3 (55.2–72.8) | 0.029 |
Total IgE, median (IQR) | 42.1 (16.2–91.6) | 71.2 (20.2–100.7) | 0.537 |
ECP (serum), median (IQR) | 12.1 (6.3–26.4) | 15.4 (8.7–28.3) | 0.656 |
Bacterial colony | |||
Pseudomonas aeruginosa | 13 | 3 | 0.671 |
Others | 12 | 1 | – |
Normal flora/no growth | 35 | 5 | – |
6MWT | |||
Rest O2 sat (%), median (IQR) | 96.0 (95.0–97.0) | 94.0 (89.0–96.5) | 0.055 |
Lowest O2 sat (%), median (IQR) | 89.5 (83.3–92.0) | 80.0 (74.0–88.0) | 0.011 |
Walk distances (m), mean ± SD | 466.1±78.0 | 359.4±113.6 | 0.001 |
DSP (m%), median (IQR) | 433.0 (340.0–482.0) | 249.0 (230.0–315.0) | 0.001 |
EID | |||
<88% | 22 | 7 | 0.030 |
≥88% | 38 | 2 | – |
A Shapiro-Wilk’s test (P>0.05) and a visual inspection of their histogram, normal Q-Q plots and box plots showed that the age, BMI, and walking distance were approximately normal distributed. These three parameters were expressed as mean and SD, with using independent Student t-test for comparison between study groups. 6MWT, 6-minute walk test; BMI, body mass index; CF, cystic fibrosis; DSP, distance-saturation product; ECP, eosinophilic cationic protein; EID, exercise-induced oxygen desaturation; FEV1, volume that has been exhaled at the end of the first second of forced expiration; FVC, forced vital capacity; IgE, immunoglobulin E; PFT, pulmonary function test.