Table 2. The relationship between DSP, characteristics, and outcomes of patients with non-CF bronchiectasis.
| Characteristics | DSP <280 (n=10) | DSP ≥280 (n=59) | P |
|---|---|---|---|
| Age (years) | 68.9±10.8 | 55.4±13.4 | 0.003 |
| Sex (M/F) | 7/3 | 32/27 | 0.281 |
| BMI | 20.9±4.5 | 22.2±3.2 | 0.286 |
| Smoking | |||
| Never | 5 | 50 | 0.024 |
| Ex/current | 5 | 9 | – |
| PFT | |||
| FVC (L) | 1.2±0.4 | 2.1±0.7 | 0.000 |
| FEV1 (L) | 0.8±0.3 | 1.6±0.7 | 0.001 |
| FEV1/FVC (%) | 64.6±12.4 | 72.0±11.4 | 0.063 |
| Total IgE | 56.9±65.2 | 70.2±72.7 | 0.607 |
| ECP (serum) | 17.8±11.1 | 21.4±29.9 | 0.708 |
| Bacterial colony | |||
| Pseudomonas aeruginosa | 3 | 13 | 0.255 |
| Others | 0 | 13 | – |
| Normal flora/no growth | 7 | 33 | – |
| 6MWT | |||
| Rest O2 sat (%) | 93.2±4.3 | 95.8±2.0 | 0.098 |
| Lowest O2 sat (%) | 81.7±10.0 | 87.7±6.6 | 0.017 |
| Walk distances (m) | 302.3±38.6 | 477.5±68.9 | 0.000 |
| Mortality | |||
| Survivors | 3 | 57 | 0.000 |
| Non-survivors | 7 | 2 | – |
6MWT, 6-minute walk test; BMI, body mass index; CF, cystic fibrosis; DSP, distance-saturation product; ECP, eosinophilic cationic protein; EID, exercise-induced oxygen desaturation; FEV1, volume that has been exhaled at the end of the first second of forced expiration; FVC, forced vital capacity; IgE, immunoglobulin E; PFT, pulmonary function test.