Table 3. Multivariate analysis for survival in stage IV esophageal cancer.
| Features | HR | 95% CI | P |
|---|---|---|---|
| Age | 1.016 | 1.012 to 1.020 | <0.001 |
| Histologic grade | <0.001 | ||
| 1 | 1 (reference) | ||
| 2 | 0.996 | 0.768 to 1.291 | |
| 3-4 | 1.253 | 0.970 to 1.618 | |
| Histology type | 0.016 | ||
| ESCC | 1 (reference) | ||
| EAC | 0.879 | 0.795 to 0.971 | |
| Others | 1.033 | 0.849 to 1.257 | |
| Number of metastatic sites | <0.001 | ||
| 1 | 1 (reference) | ||
| 2 | 1.272 | 1.150 to 1.406 | |
| 3 | 1.491 | 1.232 to 1.805 | |
| 4 | 3.190 | 1.758 to 5.787 | |
ESCC, esophageal squamous cell carcinoma; EAC, esophageal adenocarcinoma; HR, hazard ratio.