Table S3. Demographic data and characteristics of patients.
| Variables | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | Total | P |
|---|---|---|---|---|---|---|
| Number of patients [%] | 52 [26] | 65 [32] | 52 [26] | 34 [16] | 203 [100] | – |
| Sex (male, %) | 17 (32.7) | 64 (98.5) | 0 (0.0) | 22 (64.7) | 103 (50.7) | <0.001 |
| Age [years] | 39.5 [28–54.5] | 51 [30.5–60.5] | 59.5 [53–65.7] | 60.5 [54–65.2] | 55 [34–63] | <0.001 |
| Age at onset [years] | 15 [6–33.7] | 36 [9.5–53.5] | 55 [41.2–63.7] | 28.5 [13.5–49] | 36 [12–53] | <0.001 |
| Asthma duration [years] | 10.5 [2–31.5] | 4 [1–20] | 2 [1–5] | 30 [10–40] | 6 [1–25] | <0.001 |
| BMI [>28 kg/m2, %] | 10 [19.2] | 8 [12.3] | 13 [25] | 1 [2.9] | 32 [15.8] | <0.05 |
| Family history (%) | 13 (25.0) | 6 (9.2) | 9 (17.3) | 9 (26.5) | 37 (18.2) | <0.001 |
| Smoking history (%) | ||||||
| Non-smoker | 46 (88.5) | 33 (50.8) | 48 (92.3) | 16 (47.1) | 143 (70.4) | <0.05 |
| Smoker | 6 (11.5) | 32 (49.2) | 4 (7.7) | 18 (32.9) | 60 (29.6) | |
| Smoking index | 31.0 (105.0) | 326.0 (521.0) | 29.0 (146.0) | 424.0 (673.0) | 191.0 (443.0) | <0.001 |
| Sinus disease (%) | 36 (69.2) | 28 (43.1) | 17 (32.7) | 9 (26.5) | 9 (44.3) | <0.001 |
Data are presented as count (%) or mean (SD) or median (IOR). P value from one-way ANOVA, chi-squared test, and Nonparametric test (Kruskal-Wallis) among the four clusters. BMI, body mass index.