Fig 2.

Color-coded DTI maps. Patients 1 (row B), 2 (row C), and 3 (row D) show an altered organization of white matter tracts if compared with a template of healthy subjects (row A). The anterior bulging of the mesencephalon corresponds to an area of transversely oriented diffusivity located anteriorly in the interpeduncular fossa (white arrowheads). CSTs in the pons are thinned (black arrow) or not clearly recognizable, and transverse pontine fibers appear as a unique bundle displaced in the anterior part of the pons. In the medulla, CST and lemnisci are hypoplastic/atrophic and the olives are reduced in volume. The decussation of SCP (white arrow in the normal template) is absent in patients 1 and 2 and markedly thinned in patient 3 (white arrows in D). Red, green, and blue represent areas of transverse, anteroposterior, and caudocranial orientation of diffusivity and white matter, respectively.