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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2017 Aug 4;179:408–415. doi: 10.1016/j.drugalcdep.2017.06.031

Figure 2.

Figure 2

A – Locomotor effects of water (filled circle), 0.10 mg/mL quinine solution (open circle) or MDPV solutions (filled triangles) in a forced choice setting after 21-hours of fluid restriction. Abscissa: Fluid available, with water and quinine control solutions presented at the “con” point, and with MDPV concentrations expressed as mg/mL on a log scale. Ordinate: Total locomotor counts summed over 6 hours during and after 3 hour access to each fluid. Asterisks represent significant differences from water control. B – Effects of water (filled bar), 0.10 mg/mL quinine solution (open bar), and each concentration of MDPV solution (gray bars) on fluid consumption during locomotor activity assessments. Abscissa: Fluid available, with water and quinine control solutions presented at the “W” and “Q” points, respectively, and with MDPV concentrations expressed as mg/mL on a log scale. Ordinate: Total volume consumed in mL during the 3 hour access period. Asterisk represents significant difference from water control. C – MDPV intake as a function of concentration of available MDPV solutions. Abscissa: MDPV concentrations expressed as mg/mL on a log scale. Ordinate: Total intake of MDPV, expressed as mg/3 hours. Asterisks indicate significant differences from lower MDPV concentrations.