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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2017 Aug 4;179:408–415. doi: 10.1016/j.drugalcdep.2017.06.031

Figure 4.

Figure 4

A – Preference for oral MDPV solutions in a continuous access two-bottle choice procedure where the alternative fluid was 0.10 mg/mL quinine. Abscissa: MDPV concentration expressed as mg/mL on a log scale. Ordinate: Mean MDPV preference score (mL MDPV solution consumed/mL total fluid consumption, expressed as a %). Asterisk indicates significant difference from lower MDPV concentrations. B – Preference for a 1.00 mg/mL MDPV solution in a continuous access two-bottle choice procedure where the alternative fluid was 0.10 mg/mL quinine following pretreatment with saline (gray bar) or the catecholamine synthesis inhibitor MPT (hatched gray bar). Abscissa: Pretreatment regimen (saline or MPT). Ordinate: As described for panel A. Asterisk indicates significant difference from saline treatment. For both panels, dashed horizontal lines at 25% and 75% indicate thresholds for preference for the alternative fluid and preference for the MDPV solution, respectively.