Table 2. Functions ranked based on expression variability of genes.

Top 10 (green) and bottom 10 (red) functions are shown based on log fold change of expression based activity (that is, number of annotated genes present in the corresponding projected PIN), along with Δ_f, Δ_f divided (normalized) by the total number of genes annotated by the function, followed by the sample shuffling results, and the log fold change.

GO ID	Description	Δf	Normalized Δf	Δf (Sample shuffling)	Normalized Δf (Sample Shuffling)	log fold change
GO:0006342	chromatin silencing	38	0.74	-1	-0.01	0.08
GO:0006334	nucleosome assembly	-310	-3.13	-3	-0.03	0.06
GO:0045814	negative regulation of gene expression, epigenetic	17	0.25	-3	-0.04	0.04
GO:0034728	nucleosome organization	4	0.03	-3	-0.02	0.03
GO:1990138	neuron projection extension	-10	-0.20	-7	-0.14	0.03
GO:0016458	gene silencing	7	0.04	-6	-0.03	0.03
GO:0031060	regulation of histone methylation	19	0.37	-15	-0.29	0.03
GO:0065004	protein-DNA complex assembly	22	0.14	-11	-0.07	0.03
GO:0031047	gene silencing by RNA	4	0.04	-7	-0.07	0.02
GO:0071824	protein-DNA complex subunit organization	8	0.04	-3	-0.01	0.02
GO:1901379	regulation of potassium ion transmembrane transport	14	0.25	-3	-0.05	-0.12
GO:0043266	regulation of potassium ion transport	10	0.12	1	0.01	-0.12
GO:1904064	positive regulation of cation transmembrane transport	309	5.15	0	0	-0.10
GO:0019229	regulation of vasoconstriction	206	3.32	-1	-0.01	-0.10
GO:0001508	action potential	2	0.03	1	0.01	-0.09
GO:0048871	multicellular organismal homeostasis	-9	-0.08	-2	-0.01	-0.09
GO:0051148	negative regulation of muscle cell differentiation	-127	-2.49	-15	-0.29	-0.09
GO:0034764	positive regulation of transmembrane transport	3	0.03	-7	-0.07	-0.09
GO:0034767	positive regulation of ion transmembrane transport	205	2.38	5	0.05	-0.09
GO:0050891	multicellular organismal water homeostasis	-31	-0.57	-5	-0.09	-0.09