Fig 1. Schematic outline of the schedule of treatment with anti-inflammatory agents and praziquantel (PZQ), showing number of pigs per group and necropsy time points when cyst and brain samples were collected for histopathology and analysis of gene expression by quantitative RT-PCR.

The experimental groups correspond to those described in detail in Methods. EB: Evans blue; PZQ: praziquantel 100 mg/kg PO, on day 0; DEX: dexamethasone 0.2 mg/kg IM, on days –1, +1 and +3; ETN: etanercept 25 mg/pig IM on days –7 and 0.