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. 2017 Nov 30;12(11):e0188802. doi: 10.1371/journal.pone.0188802

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© 2017 Kasai et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Scatter plot for t-tau level in plasma in the control group (n = 22) and DS group (n = 21). Bars indicate median values. Levels of t-tau in the DS group were significantly higher than those of the control group (P = 0.0050). (B) Scatter plot for t-tau level in plasma in young generation (ages 14–25 years; n = 6 in the control group and 7 in the DS group), middle-aged generation (ages 26–42 years; n = 8 in the control group and 8 in the DS group), and older generation (aged older than 43 years; n = 8 in the control group and 6 in the DS group) generation. Bars indicate median values. Levels of t-tau in the DS group were significantly higher than those of the control group in the middle-aged generation and the older generation (P = 0.021 and 0.003, respectively).