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. 2017 Nov 30;12(11):e0188981. doi: 10.1371/journal.pone.0188981

Fig 4. Increased expression of fibrotic factors in Akr1b3 null I/R mice hearts.

Fig 4

RNA isolated from heart tissues from mice subjected to I/R. (A) qRT-PCR on collagens (Col1a1, Col1a2, Col3a1) and MMPs (Mmp2 and Mmp9), N = 5 mice/group. (B) Western blot analysis on RUNX2 and MMP2 expression in heart tissues subjected to I/R. N = 4/group. Error bars represent mean ± SEM. * p<0.05, unless otherwise noted.