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. 2017 Nov 30;12(11):e0188981. doi: 10.1371/journal.pone.0188981

Fig 6. β-Catenin pathway inhibitor reverses the Akr1b3 null mediated protection and mesenchymal marker expression.

Fig 6

Mice hearts were subjected to ex vivo I/R using Langendorff technique. (A) qRT-PCR on heart tissues for mesenchymal markers as indicated, N = 3. (B) qRT-PCR on heart tissues for collagen and matrix metalloproteinases as indicated, N = 3 mice/group. (C) qRT-PCR on primary CF for mesenchymal markers treated either with recombinant TGFB2 or IWR as indicated, N = 5/group. Error bars represent mean ± SEM. * p<0.05, unless otherwise noted.