Table 3. Univariate and multivariate analysis of factors affecting disease progression in 154 patients with endometrial endometrioid carcinoma.

		Metastasis		Univariate P-value	Multivariate P-value
Histological grade
	G1	8/96	(8.3%)
	G2	11/36	(30.6%)	<0.01
	G3	10/22	(45.5%)	<0.01	0.025
					(G1vs.G2+G3)
Myometrial invasion
	<1/2	9/105	(8.6%)
	≥1/2	20/49	(40.8%)	<0.01	0.088
LVSI
	Negative	6/81	(7.4%)
	Positive	23/73	(31.5%)	<0.01	0.55
p53
	Negative	7/102	(6.9%)
	Stained	22/52	(42.3%)	<0.01	0.014
ERβ
	Low	0/86	(0%)
	High	29/68	(42.6%)	<0.01	<0.01

LVSI, lymph-vascular space invasion.