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. 2017 Nov 30;12(11):e0184805. doi: 10.1371/journal.pone.0184805

Fig 2. Mean arterial pressure (MAP, A), and delta MAP (B), heart rate (HR, C) and delta HR (D) responses to chronic ICV leptin infusion in ad libitum-fed control and hypophysectomized (Hypo) non-diabetic rats.

Fig 2

*p<0.05 compared to control period; #p<0.05 compared to vehicle-treated group. Delta MAP and HR were calculated as differences between the experimental values and the average baseline values measured on the last 3 days prior to starting leptin infusion.